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Combination data with diet suggest complementary mechanisms, and reviews highlight continued medicinal-chemistry work to tune potency, selectivity, and exposure for future translational studies
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To ascertain that these findings were not merely a coincidence, we designed a second set of PYY variants containing four new mAAs and measured their solubilities (Fig
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Influences HPA axis regulation and cortisol dynamics: The hypothalamic-pituitary-adrenal (HPA) axis governs physiological stress responses through sequential CRH, ACTH, and cortisol release
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