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The constant production of pro-inflammatory cytokines creates a hostile cellular environment that damages the delicate inner mitochondrial membrane, specifically targeting cardiolipina unique lipid essential for anchoring the electron transport chain complexes
It is effective in high concentrations of H 2 O 2
Role of nuclear factor erythroid 2-related factor 2 in the oxidative stress-dependent hypertension associated with the depletion of DJ-1
Our patient was diagnosed with severe GSSD after neonatal onset, with symptoms including hemolytic anemia, hyperbilirubinemia and severe metabolic acidosis (intractable), urine-organic acid analysis results suggestive of the presence of 5-oxoprolinuria, and imaging results suggestive of central nervous system damage and developmental retardation in the infant at follow-up
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