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If the drug works without weight loss, you dont need a high dose to benefit
14.3 MOUNJARO Use in Combination with Metformin, Sulfonylureas, and/or SGLT2 Inhibitors in Adult Patients with Type 2 Diabetes Mellitus SPL UNCLASSIFIED SECTION SPL UNCLASSIFIED SECTION Add-on to metformin SURPASS-2 (NCT03987919) was a 40-week open-label trial (double-blind with respect to MOUNJARO dose assignment) that randomized 1879 adult patients with type 2 diabetes mellitus with inadequate glycemic control on stable doses of metformin alone to the addition of subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, or MOUNJARO 15 mg once weekly or subcutaneous semaglutide 1 mg once weekly
For many, the shift from weekly injections to a daily pill has made managing metabolic health much more convenient
As with all research compounds, safety data are still incomplete
