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Available from: Accessed January, 2021
It reflects elevated metabolic rate driving fat burning
Dose adjustments are made based on symptoms and sensitivity under a clinicians guidance
With both tirzepatide and semaglutide, approximately 33-40% of total weight lost consists of lean mass
Authors: Karen G Farrar University of Southern California , Los Angeles, CA, Duy Do Truveta, Inc , Bellevue, WA, Nina B Masters Truveta, Inc , Bellevue, WA, Brianna M Cartwright Truveta, Inc , Bellevue, WA After CVS Caremark made anti-obesity semaglutide the preferred formulary option in July 2025, switching from anti-obesity tirzepatide surged from 0.6% to 9.7%, representing more than a 16-fold rise
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