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Native amylin is pharmacologically active at amylin and calcitonin receptors, but it has three severe structural liabilities that make it unsuitable as a research tool: Problem 1: Amyloid aggregation
Trastuzumab deruxtecan in patients with metastatic non-small-cell lung cancer (DESTINY-Lung01): primary results of the HER2-overexpressing cohorts from a single-arm, phase 2 trial
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