There is no single timeline that fits everyone
There were over 100 metabolites detected in the intracellular extracts and 68 of them were identified by our in-house mass spectral library (Table 1)
In mice fed Se deficient diets, testicular atrophy, reduced diameter of the seminiferous tubules, osseous metaplasia, and reduced spermatogenic activity were observed: no mitotic activity in spermatogonia, reduced the number of spermatogenic cell lines (including stem cells, pachytene spermatocytes, spermatids, and maturing sperms), and higher rates of abnormal morphology of sperm were found without difference in chromosomal abnormalities in spermatocytes (85, 100)
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells
References 1) Laurindo, L.F