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prpTDP-43 A315T -UeGFP mice, the CSMN reporter line with TDP-43 pathology, allowed cell-type specific responses of CSMN to NMN treatment to be assessed in vitro
They do not replace arthritis medications like DMARDs or biologics, but can be used, with caution, in conjunction with them, only under medical supervision
Trials began late 2025 in Aventura, Florida, expanding further in 2026
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