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Psychedelics may influence KP both directly, by regulating expression or activity of rate-limiting enzymes like IDO and TDO through downstream signalling mechanisms, and indirectly, via interactions with the gut microbiome pathways that are known to govern KP flux and peripheral TRP availability [174, 219]

For the tracing 13 ,C 3 -serine was added to a final concentration of 100 M and cultured for an additional 6 h of hemin, DMF or both treatments

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Leduc-Gaudet JP, Hussain SNA, Barreiro E, Gouspillou G