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Activation of aerobic glycolysis-related bypass pathways Increased glycolysis simultaneously activates multiple self-associated bypass pathways, among which the PPP provides the raw material for purine and pyrimidine nucleotide synthesis and maintains redox homeostasis for cancer cell growth, which largely depends on the activity of glucose-6-phosphate dehydrogenase (G6PD), as it catalyzes the first step of the glucose-6-phosphate shift to the PPP [46]

MacDonald, P

Gastroenterology 135: 17101718

This experience has also highlighted the advantages of hormone therapy and the O-Shot, both of which are addressed at our local women's clinic that focuses on various women's issues