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The titles and abstracts were screened by 4 separate reviewers (M.A., A.A., B.A.K., S.T.S.) followed by full-text screening
Four literature reviews concluded GLP-1s increased bone formation, three of which found them superior to other diabetes medications
Important gaps include independent replication, validated potency methods, long-term toxicology, interaction data, broader population research, and adequately powered confirmatory trials
[1] Initial human trials showed that it retains the lipolytic properties of human growth hormone without stimulating IGF-1 production
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