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The global expansion of GLP-1 receptor agonists and related anti-obesity therapies represents a triumph of translational metabolic science

While muscle weakness is not a typical side effect, indirect issues such as nutrient deficiencies, sarcopenia, or blood glucose fluctuations may play a role

This is a nutritional intervention that reduces energy intake while maintaining nutrient adequacy and has been shown to prolong healthy lifespan in rodent and primate models [189]

Deferiprone decreased iron in the substantia nigra and raised striatal dopamine levels when given orally at 30 mg/kg in a phase 2 randomized double-blind placebo-controlled clinical trial in PD (Martin-Bastida et al., 2017)

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