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10.3390/antiox12071423 311 MatsumotoM.InoueR.TsukaharaT.UshidaK.ChijiH.MatsubaraN.et al

This validated the in vitro model as representative of age-related Leydig cell dysfunction

They bind to GLP-1 receptors throughout the body and produce a prolonged version of the natural response, dramatically reducing hunger, improving insulin sensitivity, and driving significant weight loss

The observed reduction in seminiferous tubule diameter in the PRP/PC group can be interpreted in the context of ongoing tissue remodeling, where residual degenerative changes and early fibrotic processes may contribute to tubular compaction

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