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* Primary study endpoint
a not marketed
3.4 Complications and side effects of GLP-1 RAs Common side effects associated with GLP-1 receptor agonists (GLP-1 RAs) include gastrointestinal symptoms such as nausea (2560%), diarrhea, and vomiting (515%) ( While some studies have suggested a possible association between GLP-1 RAs and acute kidney injury (AKI), this has not been confirmed and appears to occur primarily in patients with underlying risk factors such as dehydration or severe gastrointestinal symptoms (49)
The uremic toxin acrolein promotes suicidal erythrocyte death
Currently, a phase III RCT evaluating histological improvement, all-cause mortality and liver-related outcomes in patients with NASH and fibrosis is ongoing
