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Studies in mice show that sucrose and umami stimuli can promote GLP-1 secretion from taste bud-like cells, reinforcing the link between nutrient detection and enteroendocrine signaling (64)
$3.0bn in 9M CY24) Put together, Lilly's GLP-1 portfolio generated $24.8B sales in 9M CY25 and has overtaken Mercks Keytruda (#1 global drug), which generated $23.3B sales and is approaching patent expiry in 2028
As described above, the benefits of organoid and assembloid modeling are evident, but incorporating these advances into a HTS workflow remains a barrier due to scalability limitations of 3D tissue models
Metformin isnt approved by the FDA for weight loss
Tirzepatide addresses the metabolic side of that equation effectively
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