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Conclusion More than thirty years have passed since the gut hormone GLP- 1 was first shown to lower blood sugar levels in people with T2DM [152]

These EVs induce endothelial cells to release pro-inflammatory cytokines, and changes in their concentration are closely associated with disease progression

Lipophilic compounds can become trapped in the mucus rather than diffusing through to the epithelium, reducing absorption efficiency

The body's natural healing response may produce itching as part of the inflammatory cascade