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Amylin suppresses acetic acid-induced visceral pain and spinal c-fos expression in the mouse
It does not require proof of efficacy in large trials the way we typically expect from drugs, but it facilitates prescribing, and that changes things a lot, because there wont be a black market anymore
Mayford M, Baranes D, Podsypanina K, Kandel ER (1996)
Because of its extended half-life, Cagrilintide only requires a once-weekly injection
Recent studies have started investigating this aspect using both endogenous neurosteroids and their synthetic analogs
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