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Figure 1 Table 1 Included randomized controlled studies

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These compounds are highly liposoluble and stable in the body and easily interact with enzymes, nucleic acids, and other macromolecules, leading to malignant differentiation and proliferation of cells

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Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Insulin Glargine as Add-on to Metformin (With or Without Sulfonylureas) in Insulin-Naive Patients With Type 2 Diabetes (SUSTAIN 4): A Randomised, Open-Label, Parallel-Group, Multicentre, Multinational, Phase 3a Trial