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Cost-effectiveness of SGLT2is Under the assumptions of our model, use of SGLT2is was cost-effective: SGLT2i use met the AU$28,000 per QALY willingness-to-pay threshold in most one-way sensitivity and scenario analyses in both populations, and also did so in most probabilistic sensitivity analyses, especially in the secondary prevention population

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[14] The evidence base consists primarily of secondary analyses and observational data rather than randomised controlled trials specifically designed to assess antidepressant effects

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