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Figure 3 Anti-inflammatory effects Previous studies have shown that GLP-1R mimics have anti-inflammatory effects in the CNS (139141)
Moreover, the SURPASS programme demonstrated that tirzepatide 15 mg is more efficacious in glycaemic control for people with T2D compared to insulin therapies as well as GLP-1 mono-agonists including semaglutide 1 mg and dulaglutide 1.5 mg
Is that a real concern
Some are approved by the Food and Drug Administration only to treat diabetes or cardiovascular disease, but others are approved to encourage weight loss as well
Beck JD, Andreeff M , Darzynkiewicz Z, Good RA, Gupta S
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