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This feature endows the Trp metabolic axis with potential interventional value in autoimmune-related inflammation, while also indicating that its translational application requires careful evaluation of ligand spectra, receptor context, and tissue specificity
doi: 10.1016/j.cardfail.2020.04.005 47 MatsuuraTRPuchalskaPCrawfordPAKellyDP
An important role is to inactivate incretins (GLP-1 & GIP)
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