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How the Evidence Balances Heart Rate Changes against Cardiovascular Outcomes While semaglutide raises resting heart rate mildly, several trials report cardiovascular event benefits for GLP-1 receptor agonists as a class in people with established cardiovascular disease

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K., Gibb, A

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53 In both Phase 1a and 1b trials, it has been established that orforglipron does not have food or water administration restrictions and may provide a safe and effective oral treatment option for patients with T2D and other indications

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Lets tackle the how

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2021;143:e984e1010

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