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For type 2 diabetes, NICE recommends GLP-1 agonists when other treatments haven't achieved target HbA1c levels, with specific consideration for cardiovascular and renal risk factors according to NICE guideline NG28

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J Clin Endocrinol Metab, 91(3), 799805

They could also very well become more effective if administered in combination with an SGLT2 inhibitor