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placebo in 3,533 patients
The indirect comparison showed a mean difference of 6.4 kg (95% CI 11.2 to 1.7), with lower baseline weight in tirzepatide arms
These include: Parkinsons disease Kidney failure or renal disease Diabetes Peripheral nerve damage (neuropathy) Spinal cord injury Iron deficiency Low levels of iron may be a factor in RLS for some people
Coincident with this increase in knowledge has been the rise of obesity and type 2 diabetes (T2D), both associated with increased morbidity and mortality
These drugs also improve insulin sensitivity
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