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A physical exam A blood test An imaging scan If these tests show an elevated thyroid-stimulating hormone (TSH) and low levels of thyroid hormones like free T4, total T3, or free T3 it may be an indication that you have hypothyroidism, says Mayumi Endo, MD, an endocrinologist in Seattle

A patient is at a high risk of major cardiovascular events

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[23] [24] However, glucagon receptor agonism can also increase hepatic glucose output, and the net long-term metabolic effects in humans are still being defined in ongoing trials