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232 In a placebo-controlled trial in 46 patients with generalized anxiety disorder, the addition of L-theanine, at doses of 450900 mg per day, to antidepressant therapy for eight weeks improved sleep satisfaction and reduced severity of insomnia in those with mild sleep-related symptoms

1 2 3 4 5 6 "Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics"

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For example, one study found that after taking 1,000 mcg of oral vitamin B12, only about 1.3% (13 mcg) is absorbed into the bloodstream