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Managing Side Effects: Hydration and Drink Selection Gastrointestinal side effects are among the most commonly reported adverse reactions to Mounjaro, particularly during the initial weeks of treatment and following dose increases

However, while ER responses were not affected by SPHKAP knockdown, we detected a delay in the mitochondrial Ca 2+ response peak time in SPHKAP RNAi versus Control RNAi-treated WT INS-1 832/3 cells (Supplementary Fig