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Lipidation additionally induces concentration-independent liraglutide multimerization, resulting in a six- to eight-fold increase in size
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A comprehensive analysis of 43,365 individuals from two US healthcare databases indicated that GLP-1 RAs do not elevate the risk of pulmonary aspiration during upper gastrointestinal endoscopy in patients with T2DM when compared to SGLT-2 inhibitors, yielding a pooled risk ratio of 0.98 (95% CI, 0.73 to 1.31) among GLP-1 RA users
The mean age ranged from 52.3 to 60.1 years, the mean diabetes duration ranged from 6.6 to 9.9 years, the mean HbA1c level ranged from 7.5 to 9.3%, the mean FPG ranged from 8.80 to 10.8 mmol/L, the mean BMI ranged from 31.3 to 34.9 kg/m 2 , the mean SBP ranged from 127.8 to 134 mmHg, and the mean DBP ranged from 77.33 to 82 mmHg
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