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The bulk of clinical evidence about BBB breakdown is derived from postmortem human brain tissue analyses, which inherently limits our ability to assess real-time dysfunction or track disease progression [27, 309]

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This process adds a 4-phosphopantetheinyl moiety, a prosthetic group required for ACPs biological activity

The real limitations are equally worth stating plainly

n 20 (indication of the mean value and the standard deviation) Blank value: 1.50 0.47 mU Value after incubation: 1.99 0.15 mU glucose-6-phosphate dehydrogenase and glutathione reductase from erythrocytes of 22 patients were examined in vitro