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Tirzepatide, a dual GLP-1 and GIP receptor agonist, works by slowing gastric emptying and reducing hunger signals in the brainbut these same mechanisms can alter how your body regulates temperature
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The post says itching occurs in a small subset of semaglutide users at low frequency, and that most published adverse event summaries rank pruritus as rare to uncommon, appearing in fewer than 5% of treated patients in major trials
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