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But "safe" comes with footnotes, and those footnotes matter
J Neurosci Res 79:509521 Carruthers BM, Jain AK, De Meirleir KL, Peterson DL, Klimas NG, Lerner AM, Bested AC, Flor-Henry P, Joshi P, Powles ACP, Sherkey JA, van de Sande MI (2011) Myalgic encephalomyelitis/chronic fatigue syndrome
Under normal physiological conditions, up to about 9098% of cellular glutathione is in the reduced GSH form, and a shift toward higher GSSG levels is widely used as an indicator of oxidative stress and impaired cellular health
When levels are low, it can lead to fatigue, brain fog, low mood, and general weakness
Other signal transduction systems and metabolic pathways involved in the MGB-based cause of depression include the endocannabinoid system, CAMKII-CREB and MAPK signaling, and glycerophospholipid metabolism
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