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K., Sirasanagandla, S., et al
doi:10.1210/jc.2006-1610 Mongongu C, Coudor F, Domergue V, Ericsson M, Buisson C, Marchand A
Joint discomfort: Elevated GH can cause joint stiffness, achiness, or mild pain
Key Features: Mimics ghrelin to increase GH pulse amplitude Does not significantly raise ACTH, prolactin, or cortisol Very low risk of water retention, appetite spikes, or gynecomastia Well-tolerated in both men and women As a standalone peptide, Ipamorelin can modestly boost GH output
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