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One of the critical components in the synthesis of pH sensitive liposome is 1,2-dioleoyl-sn-glycero-3-phosphoenthanolamine (DOPE), however, DOPE being a non-bilayer lipid with a cone-shaped structure, does not form a bilayer alone
The function of the protective group is to prevent side reactions of amino acids during the condensation process
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cagrilintide was designed to overcome both limitations while retaining and enhancing amylin receptor pharmacology
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