the protective concentration of senegenin against oxidative damage was determined using the CCK-8 assay, and the effects of senegenin on the expression of Keap1/Nrf2 and PINK1/Parkin, key signaling pathways involved in oxidative stress and mitochondrial damage, were analyzed
More importantly, this treatment approach was safe, with an extremely low rate of major complications (1.5%) and almost zero treatment-related mortality (tumor-related mortality of only 0.2%)
31 , 375390.e311 (2020)
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