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Structure-activity relationship of a pyrrole based series of PfPKG inhibitors as anti-malarials

53 In both Phase 1a and 1b trials, it has been established that orforglipron does not have food or water administration restrictions and may provide a safe and effective oral treatment option for patients with T2D and other indications

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To maximize fertility, it is recommended that both men and women restrict alcohol intake to no more than two or three alcoholic drink equivalents spaced out over a week

We need further research to understand the full potential of GLP-1 RAs and all the intricacies of their MOA for optimal clinical use