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When ingested they compete with cholesterol for absorption in the intestines, thereby reducing the amount of cholesterol absorbed into the body (36)

This peptide plays several crucial roles in how your body processes food: It slows down gastric emptying (how quickly food moves from your stomach to your intestines) It increases feelings of fullness after eating It reduces appetite signals in your brain It helps regulate blood sugar by stimulating insulin release In essence, these medications trick your body into thinking you're fuller than you actually are, while simultaneously putting the brakes on digestion so that feeling of satisfaction lasts longer

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A GI provider like Oshi Health can diagnose whats causing your symptoms and can develop a comprehensive, personalized treatment plan

They were given different doses of retatrutide or a placebo once a week for 48 weeks