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Data availability The review data will be shared upon request from the corresponding author

R: Circadian Considerations: Nocturne (30-60 min pre-sleep): Optimal Synchronize with natural GH pulse higher Improve deep sleep quality Maximize overnight anabolic effects Post-exercise: Effective alternative Anabolic window utilized Muscle repair/growth Timing: Immediately to 30 minutes post-workout Morning fast: Advanced option Higher GH fasting state Lipolysis Synergy Requires specific protocol Receptor desensitization in prolonged studies

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Age-related changes in brain energetics and phospholipid metabolism

This combination targets two distinct GH-promoting mechanisms