How AOD-9604 Avoids IGF-1 Stimulation Insulin-like growth factor 1 (IGF-1) is a hormone primarily produced in the liver in response to growth hormone receptor activation
This reaction occurs mostly by an enzymatically catalyzed addition by a glutathione-S transferase (GST)
For localized injuries like a specific tendon, ligament, or muscle tear, subcutaneous injection near the injury site provides the highest local concentration and most predictable results
In 1993, the first large, randomized, double-blind, primary prevention trial to investigate the potential cancer prevention benefits of supplementing with vitamin E, selenium and -carotene was conducted, and the cocktail has been found to dramatically lower mortality from gastric cancer (159)
doi: 10.1002/iub.2046 129 VinuNavarroJHerrero-CerveraAGarca-CubasMAndrs-BlascoIMartnez-HervsSet al