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Once the tumour became arrested in the palbociclib-treated group, mice were further randomized to receive either RSL3 (50 mg kg 1 , five times per week for 2 weeks) or the vehicle, resulting in four experimental groups: vehicle, RSL3, palbociclib and palbociclib + RSL3
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In other words, it indicates a pseudo-Jahn-Teller effect that both brings the reagents closer and cleaves the Co-C bond
Its relationship with nitric oxide is interesting it doesn't just crank NO up or shut it down
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