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Numerous types of oxPL have been identified in oxidized LDL (oxLDL) particles and many of them exhibit biological activity and exert key effects in the development of atherosclerotic lesions in the vasculature
Ascorbate is the cofactor for Cu + dependent monooxygenases and for several 2-oxoglutarate and Fe 2+ dependent dioxygenases (2OG-oxygenases)
and glutaredoxins, which use GSH to repair oxidised protein thiols
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