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Biochem Pharmacol 197:114929 Rah B, Rather RA, Bhat GR, Baba AB, Mushtaq I, Farooq M et al (2022) JAK/STAT signaling: molecular Targets, therapeutic Opportunities, and limitations of targeted inhibitions in solid malignancies

Activation of the coagulation system: This can lead to hypercoagulation and vascular blockage

Regarding the question of what these results tell us about dietary supplementation, this study serves as a reminder of the importance of seeking professional advice when taking supplements

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This can be solved with the right diet and training protocol but is easiest managed by Metformin