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Studies reporting multiple brain locations were analyzed as sub-studies, and when bilateral measures were available, the left and right voxels were averaged

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Acetyl L-Carnitine contains a functional dose of 500 mg of acetyl L-carnitine

One well-documented interaction is with certain anti-epileptic drugs: high-dose pyridoxine may reduce the plasma levels of phenytoin and phenobarbital by enhancing their hepatic metabolism, potentially diminishing their anticonvulsant efficacy