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Article history: Received 27 September 2021
Patient-reported outcomes following treatment with the human GLP-1 analogue liraglutide or glimepiride in monotherapy: results from a randomized controlled trial in patients with type 2 diabetes
These drugs have significance in obesity treatment, particularly in situations where more broadly acting medications are not suitable for the patient
This longer activity window also supports consistent week-to-week signaling , which is why gradual titration is often emphasized early on to improve tolerability while establishing a stable maintenance routine
Patients with variants predicting rapid adaptation can confidently uptitrate faster, while those with slower adaptation benefit from extended micro-dosing protocols
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