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Potency loss is minimal (less than 5%) during the first 28 days at correct refrigeration temperature, but accelerates rapidly if the vial experiences temperature excursions above 8C or light exposure
These include moving beyond single biomarkers to adopt multidimensional assessments that combine biomarkers, neuroimaging, digital phenotyping, and behavioral measures [580, 582, 610, 638]
At 52 weeks, the group continuing tirzepatide experienced an additional 5.5% weight reduction, while the group who switched to the placebo regained 14% of their body weight
it could go faster, but its okay