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Examining the risk of depression or self-harm associated with incretin-based therapies used to manage hyperglycaemia in patients with type 2 diabetes: a Cohort Study using the UK Clinical Practice Research Datalink

Long-term Comparative Effectiveness of Once-weekly Semaglutide Versus Alternative Treatments In a Real-world Us Adult Population with Type 2 Diabetes: a Randomized Pragmatic Clinical Trial

Retatrutide Availability & Timeline Retatrutide is expected to receive FDA approval in mid-2027 with pharmacy availability in late 2027

A large review found that using GLP-1 drugs increases the chance of gallbladder or bile duct disease, especially at higher doses, for longer periods, or when used for weight loss

It can also reduce the chances of conceiving with certain fertility treatments, such as in vitro fertilization (IVF)