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Acetyl-L-Carnitine can be used to fight fatigue in individuals with MS, with some research subjects reporting significant reductions in fatigue and an overall improvement in their quality of life

Given the shortages and often limited insurance coverage, online and brick-and-mortar pharmacies are offering compounded versions of the drugs

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Exclusion criteria included: Pregnancy, lactation, severe cardiovascular disease, having other infections such as human immunodeficiency virus (HIV), history of taking L-carnitine supplement in the last month, requires intensive care units (ICU), patients with high and critical disease severity, taking anti-inflammatory drugs out of the patient's medication regimen and the patient's unwillingness to continue cooperating with investigators