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Avoid Extreme Calorie Restriction: Hormones can get disrupted and period irregularities to occur as a result of extreme weight loss
Various body systems- gastrointestinal tract motility, kidney function, and vision ability, to name a few, have been subjected to ongoing chronic low-grade inflammatory changes over several years
doi: 10.1016/j.cell.2012.03.042 14 EntezariS.HaghiS
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This causes leakage of cellular contents and a strong local inflammatory response
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