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We need much bigger, better-designed studies before we can call this a proven treatment

Weight loss frequently correlates with increased mobility, improved exercise tolerance, and greater engagement in physical activity [11]

10.1210/en.2004-1389 Endocrinology 49 EverardA.LazarevicV.DerrienM.GirardM.MuccioliG

Frailty has been associated with poor patient outcomes

Healthcare providers should assess the risk versus benefit for each patient, particularly those with obesity and diabetes, considering the potential protective effects of weight loss on renal health