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They modulate redox-sensitive pathways such as those mediated by mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase (PI3K), and some tyrosine phosphatases
Purity is verified by HPLC and mass spectrometry to 99%
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Mechanistic studies would be strengthened by isoform-specific NOS experiments, FAK or paxillin pathway inhibition, VEGFR2 pathway modulation, direct measurement of endothelial and fibroblast markers, and rescue experiments that test whether blocking one pathway prevents downstream effects
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