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Hypoxia primarily regulates glucose metabolism by influencing the expression of glucose transporters and glycolytic enzymes and suppressing the tricarboxylic acid (TCA) cycle pathway
Its mechanisms of action have been primarily explored in non-clinical studies involving animal models, cell cultures, and limited human cohorts
Zheng S, Deng Z, Chen F, Zheng L, Pan Y, Xing Q, et al
Oxidative stress accelerates the aging process and the development of neurodegenerative diseases like Alzheimers and Parkinsons
Acta 1863 , 881894 (2018)
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