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Suspected adverse reactions to any medication should be reported via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
However, the landmark SURMOUNT-5 trial (published in mid-2025), which compared the two medications head-to-head, clarified the clinical reality: Total Weight Loss: Tirzepatide drives significantly greater total weight loss (averaging over 20%) compared to semaglutide (averaging roughly 14%)
Spinal manipulation : May provide modest benefit for some patients with acute low back pain
2023, doi:10.3390/antiox12051094 4 Campolo J, et al
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